Palladium on carbon CAS 7440-05-3

Discover Aure Chemical's Premium Palladium on Carbon Supply

Palladium on carbon (Pd/C), CAS No. 7440-05-3, is the most widely used heterogeneous palladium catalyst in pharmaceutical, fine chemical, agrochemical, and specialty material industries. Supplied by Aure Chemical as a black to dark gray powder with palladium loadings typically ranging from 1% to 10% on high-surface-area activated carbon, this versatile catalyst delivers exceptional activity, selectivity, and poison resistance under mild conditions. Its ability to efficiently reduce alkenes, alkynes, nitro groups, carbonyls, aromatic rings, and to perform debenzylation of protecting groups makes it indispensable for API synthesis, natural product derivatization, and bulk intermediate production. Aure Chemical offers tightly controlled metal dispersion, multiple carbon support grades (wood, coconut, peat), and stringent quality assurance to ensure batch-to-batch reproducibility, maximum turnover, and easy recovery for cost-effective, scalable industrial processes worldwide.

Basic Information of Palladium on Carbon

Aure Chemical supplies Palladium on Carbon as a premium heterogeneous Pd catalyst with optimized metal dispersion and support properties for reliable hydrogenation and hydrogenolysis applications.

CAS No.	7440-05-3 (Pd); support material varies
EC No.	231-115-6 (Pd)
Chemical Formula	Pd on activated carbon
Molecular Weight	106.42 g/mol (Pd basis)
Appearance	Black to dark gray powder
Odor	Odorless
Melting point	Not applicable (support decomposes; Pd melts at 1555 °C)
Boiling point	Not applicable
Density	approx. 0.4–0.8 g/cm³ (bulk density, loading-dependent)
Solubility	Insoluble in water and organic solvents
Nature (hazards)	Combustible solid (carbon support), may cause respiratory irritation when dust is inhaled, harmful if dust is inhaled in large quantities
RIDADR	Not regulated (non-hazardous for transport in many classifications; consult SDS for specific handling)
Chemical Structure

Aure Chemical provides customizable Pd loadings (1%, 5%, 10% most common), support types (wood, coconut, peat-based carbon), pre-treatments (reduced, oxidized, sulfided), and moisture levels to match your specific hydrogenation or process requirements.

Primary Applications of Palladium on Carbon

Palladium on Carbon is the benchmark heterogeneous catalyst for selective hydrogenation and hydrogenolysis in high-value chemical manufacturing.

1. Hydrogenation of Alkenes & Alkynes
   Provides rapid and selective reduction of C=C and C≡C bonds in complex molecules, ideal for pharmaceutical intermediates and natural product derivatives with minimal over-reduction.

2. Aromatic Ring Hydrogenation
   Efficiently saturates benzene rings and heterocycles under moderate pressure and temperature, producing cyclohexane-based building blocks for agrochemicals, polymers, and performance chemicals.

3. Nitro Group Reduction to Amines
   Delivers high-yield, clean conversion of aromatic and aliphatic nitro compounds to primary amines, a critical step in dyes, pesticides, and active pharmaceutical ingredient manufacturing.

4. Debenzylation & Protecting Group Removal
   Enables selective hydrogenolysis of O-benzyl, N-Cbz, and related protecting groups with excellent functional group tolerance, essential for multi-step synthesis in medicinal chemistry.

5. Carbonyl & Imine Reduction
   Catalyzes selective hydrogenation of ketones, aldehydes, and imines to alcohols or amines, offering superior selectivity in the presence of other reducible groups.

6. Fine Chemical & API Manufacturing
   Widely applied in GMP processes for reduction and deprotection steps of active pharmaceutical ingredients, providing scalability, easy catalyst removal, and high reproducibility.

Why Choose Aure Chemical for Your Palladium on Carbon Supply?

Partner with Aure Chemical for Palladium on Carbon to access industry-proven catalytic performance, customization flexibility, and secure precious metal supply for your hydrogenation processes.

• Optimized Pd Dispersion & Activity
  Advanced impregnation technology ensures uniform Pd particle size and high active surface area for maximum turnover frequency and product selectivity.

• Custom Catalyst Formulations
  Tailored Pd loadings, support types, reduction states, and additives to precisely match your substrate, solvent system, and reaction conditions.

• Consistent Batch-to-Batch Reproducibility
  Rigorous in-house testing (ICP, BET, XRD, activity assays) guarantees low variation and predictable scale-up performance.

• Secure Palladium Supply Chain
  Responsible sourcing, strategic inventory, and transparent pricing mitigate market volatility and ensure uninterrupted availability.

• Technical & Regulatory Support
  Expert guidance on catalyst activation, poison mitigation, recycling, and full documentation (COA, REACH, SDS) for seamless integration into GMP and fine chemical operations.

Hazards Classification

• GHS Classification: Specific Target Organ Toxicity, Single Exposure (respiratory tract irritation) (Category 3); Combustible dust hazard; Aquatic Chronic (Category 3)

• Hazard Statements: H335: May cause respiratory irritation; H413: May cause long lasting harmful effects to aquatic life

• UN Number: Not regulated

• Hazard Class: Not classified as hazardous for transport

• Packing Group: Not applicable