Aure Chemical: Your Reliable Partner for High-Quality Boron Trifluoride Tetrahydrofuran Complex (BF₃-THF)
Aure Chemical is a trusted supplier of Boron Trifluoride Tetrahydrofuran Complex (BF₃-THF), a widely recognized and highly effective Lewis acid catalyst. This clear, colorless liquid provides a stable and easily handled source of Boron Trifluoride (BF₃), making it an invaluable reagent for a vast array of organic synthesis applications, from academic research to industrial production.
Product Overview & Key Properties
Boron Trifluoride Tetrahydrofuran Complex (CAS No. 462-34-0) is characterized by its significant properties:
| CAS No.: | 462-34-0 |
| EC No.: | 207-325-9 |
| Linear Formula: | C₄H₈BF₃O |
| Molecular Weight: | 139.91 |
| Appearance: | Transparent Liquid |
| Melting Point: | 11-13 °C (lit.) |
| Boiling point | 180 °C (lit.) |
| Density: | 1.268 g/mL at 25 °C (lit.) |
| Solubility: | Miscible with dimethyl formamide. |
| Flash Point: | 198 °F |
| RIDADR: | UN 3265 8/PG 2 |
| Nature: | Strong Lewis acid. |
| Chemical Structure: |  |
Its precise composition and catalytic strength make it an essential tool for chemists requiring efficient and selective Lewis acid catalysis.
Main Functions and Applications of Boron Trifluoride Tetrahydrofuran Complex
The potent Lewis acidity and broad utility of Aure Chemical's Boron Trifluoride Tetrahydrofuran Complex enable its diverse applications across various advanced chemical syntheses:
Catalyst for Organic Reactions: This complex is a cornerstone in organic chemistry, serving as a versatile and efficient Lewis acid catalyst. It promotes a wide range of reactions, including Friedel-Crafts alkylation and acylation, Diels-Alder reactions, aldol reactions, rearrangements, and epoxide openings, making it indispensable for C-C bond formations and complex molecular architectures.
Preparation of Pharmaceutical Products: Due to its high reactivity and selectivity, BF₃-THF is commonly employed as a catalyst in the synthesis of various pharmaceutical products. This includes facilitating key steps in the production of complex drug molecules such as cephalosporins and fluoroquinolones, where precise catalytic control is paramount.
Preparation of Boranes and Targeted Drugs: Beyond its role as a catalyst, BF₃-THF is an important raw material for the synthesis of various boranes (boron-hydrogen compounds) and the development of boron-containing targeted drugs. This includes applications in areas like Boron Neutron Capture Therapy (BNCT) and other novel boron-based therapeutics.
Pharmaceutical Intermediate: In the pharmaceutical field, BF₃-THF is also directly utilized as a crucial pharmaceutical intermediate. Its ability to readily participate in various transformations makes it a valuable building block for synthesizing more complex drug candidates and active pharmaceutical ingredients (APIs).
Why Choose Aure Chemical for Your Boron Trifluoride Tetrahydrofuran Complex Needs?
Aure Chemical is committed to delivering excellence and reliability in chemical supply. When you choose us for your Boron Trifluoride Tetrahydrofuran Complex requirements, you benefit from:
Assured Purity & Performance: Our BF₃-THF undergoes stringent quality control to ensure high purity and consistent catalytic activity, vital for sensitive organic reactions and industrial processes.
Reliable Supply Chain: We maintain a robust and efficient global supply chain, ensuring timely and secure delivery of this valuable reagent.
Technical Expertise: Our knowledgeable team is always available to provide comprehensive support and answer any technical questions you may have regarding product application, handling, and safety.
Commitment to Quality & Safety: We adhere to the highest quality control, safety, and environmental standards throughout our operations, from manufacturing to distribution.
Partner with Aure Chemical for a seamless and dependable supply of high-quality Boron Trifluoride Tetrahydrofuran Complex. We are ready to assist you in finding the perfect solution for your specific application requirements.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
