Amino-PEG7-alcohol CAS 1425973-14-3

High-Purity Amino-PEG7-alcohol CAS 1425973-14-3 from Aure Chemical

Amino-PEG7-alcohol (CAS 1425973-14-3), also known as NH2-PEG7-OH, is a monodisperse bifunctional polyethylene glycol derivative featuring a terminal primary amine and a terminal hydroxyl group connected by a heptaethylene glycol spacer. This bifunctional structure makes it a useful molecular linker intermediate in organic synthesis and bioconjugation applications.

It is commonly employed in pharmaceutical research for the construction of PEGylated compounds, PROTACs, and antibody-drug conjugates where a defined hydrophilic spacer is needed. Aure Chemical provides reliable sourcing support for this fine chemical intermediate along with essential documentation for global customers.

Basic Information

CAS No.	1425973-14-3
EC No.	Not available
Linear Formula	H₂N-(CH₂CH₂O)₇-H
Molecular Weight	325.40 g/mol
Appearance	Colorless to light yellow viscous liquid or oily liquid
Melting Point	Not available (typical reference)
Boiling point	427.3 ± 40.0 °C (Predicted)
Density	1.088 ± 0.06 g/cm³ (Predicted)
Solubility	Soluble in water and polar organic solvents such as DMSO, DMF, and DCM
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture and light. Recommended storage at 2-8°C.
Chemical Structure

Key Applications

• PEG linker intermediate: Serves as a defined seven-unit PEG spacer with amino and hydroxyl end groups for assembling PROTAC molecules and non-cleavable ADC linkers.

• Bioconjugation research: The primary amine enables efficient coupling to carboxylic acids and activated esters, while the hydroxyl terminus supports additional functionalization of biomolecules.

• Fine chemical intermediate: Functions as a building block for introducing hydrophilic polyether chains into complex organic structures in specialty synthesis projects.

• Process development: Supports laboratory and pilot-scale efforts to optimize synthetic routes that require precise PEG-based linkers with controlled spacer lengths.

• Laboratory research: Widely used in medicinal chemistry laboratories for exploring PEGylation strategies and developing functional conjugates with tailored hydrophilic properties.

Why Work with Aure Chemical for Amino-PEG7-alcohol

• Consistent product quality: High-purity Amino-PEG7-alcohol is sourced through established channels with routine quality coordination to meet fine chemical specifications.

• Flexible global supply: We support laboratory, pilot, and bulk procurement needs with stable export logistics and flexible shipping arrangements worldwide.

• SDS and COA support: Comprehensive product documentation including SDS and COA is available upon request to facilitate regulatory review and international procurement.

• Packaging and technical service: Responsive technical communication and assistance with appropriate packaging selection based on order quantity and product characteristics.

Packaging and Storage

• Packaging: Available in small laboratory quantities in sealed containers or sample bottles; larger volumes supplied in suitable HDPE drums. Customized liquid packaging options can be arranged based on specific requirements.

• Storage: Store in a tightly closed container in a cool, dry, well-ventilated place. Protect from moisture and light. Long-term storage recommended at 2-8°C.

• Handling of opened containers: After opening, minimize exposure to air and moisture. Use the contents promptly and reseal the container tightly to maintain product integrity.

Safety and Handling

• General handling: Work in a well-ventilated area or chemical fume hood. Follow standard laboratory practices for handling organic compounds with amine and alcohol functional groups.

• Personal protection: Wear suitable protective gloves, safety goggles, and protective clothing to prevent skin and eye contact during handling.

• Documentation review: Consult the current Safety Data Sheet (SDS) before handling, storage, or transportation to ensure appropriate precautions are observed.