2-(tert-Butylamino)ethanol (TBAE) CAS 4620-70-6

2-(tert-Butylamino)ethanol CAS 4620-70-6 for Organic Synthesis Intermediates

2-(tert-Butylamino)ethanol, also known as TBAE, is a sterically hindered secondary amino alcohol intermediate containing tert-butylamino and hydroxyl functionality. Its ethanolamine-derived structure makes it useful in organic synthesis routes where secondary amine structure, steric influence and alcohol functionality are required for further derivatization.

This product may be used in pharmaceutical intermediate synthesis, fine chemical synthesis, specialty organic intermediate preparation and downstream amine- or hydroxyl-based transformations. In B2B sourcing, buyers usually need to confirm assay, water content, appearance, color, related amine impurities, residual solvents, physical state, storage conditions, packaging, transport classification and documentation availability before purchase.

Basic Information

The following information is provided as general product reference. Final specification, test method, appearance, physical state, packaging, storage conditions and documentation should be confirmed according to the actual batch and supplier information.

CAS No.	4620-70-6
EC No.	225-034-5
Linear Formula	(CH3)3CNHCH2CH2OH
Molecular Weight	117.19
Appearance	White or colorless to light yellow powder, lump or low-melting material; physical state should be confirmed according to supplier specification and actual temperature conditions.
Melting Point	41–43°C (lit.)
Boiling Point	176–177°C (lit.)
Density	0.867 g/mL at 25°C (lit.)
Solubility	Soluble in water and many common organic solvents
Storage Conditions	Store in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture, heat, oxidizing agents and incompatible materials. Specific storage requirements should be confirmed according to SDS and supplier recommendation.
Chemical Structure

Key Applications

• Organic synthesis intermediate: Used as a sterically hindered secondary amino alcohol building block for introducing tert-butylaminoethyl functionality in downstream synthesis.

• Pharmaceutical intermediate synthesis: May be used as a starting material or intermediate in selected pharmaceutical intermediate routes, subject to specification and process requirements.

• Fine chemical intermediate: Suitable for specialty chemical synthesis where secondary amino alcohol structure, steric effects, polarity adjustment or further functionalization is required.

• Ethanolamine derivative: The tert-butylamino group and hydroxyethyl structure may support selected routes requiring amino alcohol chemistry, salt formation or hydroxyl-based derivatization.

• R&D and process evaluation: Can support laboratory evaluation, route screening and process development for organic synthesis projects.

• Further derivatization: The hydroxyl group and secondary amine functionality may be involved in acylation, alkylation, esterification, etherification, salt formation or other downstream transformations depending on the synthesis route.

Sourcing and Documentation Support

• Specification confirmation: Assay, appearance, color, water content, related amine impurities, residual solvents and physical state can be reviewed according to buyer requirements and supplier confirmation.

• COA and SDS support: COA and SDS may be provided for confirmed products, subject to product, batch and supplier confirmation.

• Packaging review: Packaging options can be checked according to product properties, physical state, order quantity, odor, moisture sensitivity, storage requirements and transport classification.

• Export and logistics discussion: Shipment feasibility, dangerous goods classification, trade term and destination requirements should be confirmed case by case before quotation or shipment.

Packaging and Logistics Considerations

2-(tert-Butylamino)ethanol should be packaged according to physical state, moisture sensitivity, order quantity, storage conditions, supplier specification and transport route. Because the product has a relatively low melting point, its physical state may vary depending on temperature and batch condition.

Packaging may include small bottles, small bags, sealed containers, cartons, fiber drums with inner liner or other suitable formats, subject to supplier confirmation. For amino alcohol products, packaging tightness, moisture protection, odor control and storage conditions should be reviewed before shipment.

Sea, air, courier, LCL or FCL shipment feasibility should be evaluated case by case according to the latest SDS, transport classification, package size and destination requirements. Import clearance, local duties, taxes and destination compliance should be confirmed by the buyer or their appointed import agent.

Common trade terms may include FOB China port, FCA warehouse, CFR/CIF destination port or DAP destination where applicable. Final shipment arrangement depends on product classification, order quantity, destination and buyer import capability.

Safety and Storage Information

The following safety information is for general reference only. Final hazard classification, handling requirements, storage conditions and transport conditions must be confirmed according to the latest SDS and shipment documents.

• Handling: Handle in a well-ventilated area with appropriate personal protective equipment and avoid direct contact with skin, eyes and clothing.

• Storage: Keep the container tightly closed and store in a cool, dry and well-ventilated place. Protect from moisture, heat, oxidizing agents and incompatible materials.

• Transport confirmation: Transport classification, labels and packaging requirements should be verified according to the latest SDS, dangerous goods classification report or shipment documents.

Related Applications

2-(tert-Butylamino)ethanol belongs to the ethanolamine and amino alcohol derivatives segment because of its secondary amino alcohol and hydroxyethyl structure. It is also related to tertiary amino alcohols and hindered amine bases where buyers compare sterically influenced amine structures for organic synthesis.

This product is part of Aure Chemical’s broader amine derivatives for API synthesis and specialty chemical intermediates portfolio.

Inquiry Information

To request a quotation for 2-(tert-Butylamino)ethanol CAS 4620-70-6, please provide the required quantity, target specification, destination port or delivery address, preferred trade term, packaging requirement and required documents such as COA or SDS.