1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine CAS 57227-28-8
Aure Chemical Supplies 1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine CAS 57227-28-8 for Specialty Synthesis
1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine is a chloroalkyl and hydroxyethyl substituted piperazine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure contains a piperazine ring with one chloropropyl side chain and one hydroxyethyl side chain, providing both chloroalkyl functionality and alcohol functionality for downstream transformation.
This compound may be evaluated when a chloropropyl hydroxyethyl piperazine structure or multifunctional piperazine intermediate is required in organic synthesis. Aure Chemical supports specification confirmation, documentation review, and sourcing feasibility evaluation based on the agreed product grade, supplier batch, quantity, and destination market.
Basic Information
| CAS No. | 57227-28-8 |
|---|---|
| EC No. | Not available |
| Linear Formula | C9H19ClN2O |
| Molecular Weight | 206.71 |
| Appearance | Colorless to light yellow liquid or low-melting solid |
| Melting Point | Not available (typical reference) |
| Boiling point | Not available (typical reference) |
| Density | Not available (typical reference) |
| Solubility | Soluble in common organic solvents |
| Storage Conditions | Keep in a cool, dry place, sealed tightly, protected from light and moisture |
| Chemical Structure | ![]() |
Key Applications
Organic synthesis intermediate: Can be used as a chloropropyl hydroxyethyl piperazine intermediate in selected organic synthesis routes involving nucleophilic substitution, alcohol derivatization, or further functionalization.
Fine chemical synthesis: May be evaluated in the preparation of specialty compounds and functionalized piperazine derivatives.
Pharmaceutical intermediate: Used as a piperazine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.
Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving chloroalkyl or hydroxyethyl piperazine structures.
Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects where multifunctional piperazine functionality is required.
Related Heterocycle Intermediates
1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine CAS 57227-28-8 belongs to Aure Chemical's piperazine derivatives for API building blocks series within our broader heterocycle derivatives for pharmaceutical intermediates portfolio.
Buyers sourcing chloroalkyl or hydroxyethyl piperazine derivatives may also review related piperazine intermediates such as 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride CAS 2031-23-4, 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, and 1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0.
For related chloroalkyl or hydroxyethyl nitrogen heterocycles outside the piperazine series, buyers may also compare 4-(3-Chloropropyl)morpholine CAS 7357-67-7, 1-(3-Chloropropyl)piperidin-4-ol CAS 145285-36-5, and Aure Chemical’s piperidine derivatives for specialty chemical synthesis.
Aure Chemical: Your Reliable Sourcing Partner
Specification confirmation: Aure Chemical supports product identity, purity, appearance, and specification review based on the agreed grade and available supplier documentation.
Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.
SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.
Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.
Packaging, Logistics & Compliance Capabilities
Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.
Packaging Options
- 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
- 100 kg / 200 kg steel or HDPE drums
- 500 kg / 1000 kg IBC containers
- Bulk liquids in ISO tank containers
- Customized packaging upon request
Transportation Modes
- Sea freight (FCL / LCL)
- Air freight for selected products
- Road and rail transportation
- Dangerous & non-dangerous cargo handling
- Incoterms: EXW, FOB, CFR, CIF, DAP, DDP
Storage & Handling
- Dry, cool, and well-ventilated warehouses
- Segregation by hazard class
- FIFO inventory management
- Temperature-controlled storage if required
- Regular inspection & labeling control
Documentation & Compliance
- Safety Data Sheet (SDS)
- Certificate of Analysis (COA)
- Dangerous Goods Declaration (DGD)
- Packing List & Commercial Invoice
- IMDG / IATA / ADR compliant labeling
For packaging customization or logistics consultation, please contact us.


