1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0
Aure Chemical Supplies 1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0 for Specialty Synthesis
1-(2-Hydroxyethyl)-4-methylpiperazine is a hydroxyethyl-substituted N-methyl piperazine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure combines a piperazine ring with one methyl-substituted nitrogen and one hydroxyethyl side chain, providing both tertiary amine character and alcohol functionality for downstream transformation.
This compound may be evaluated when a hydroxyethyl methylpiperazine structure or alcohol-functional piperazine intermediate is required in organic synthesis. Aure Chemical supports specification confirmation, documentation review, and sourcing feasibility evaluation based on the agreed product grade, supplier batch, quantity, and destination market.
Basic Information
| CAS No. | 5464-12-0 |
|---|---|
| EC No. | Not available |
| Linear Formula | C7H16N2O |
| Molecular Weight | 144.22 |
| Appearance | Colorless to light yellow low-melting solid or viscous liquid |
| Melting Point | 39-41 °C (lit.) |
| Boiling point | 54-55 °C at 0.5 mbar (lit.) |
| Density | 1.003 g/cm³ (Predicted) |
| Solubility | Soluble in water and polar organic solvents |
| Storage Conditions | Sealed in dry conditions at room temperature, protected from moisture |
| Chemical Structure | ![]() |
Key Applications
Organic synthesis intermediate: Can be used as a hydroxyethyl methylpiperazine intermediate for introducing alcohol-functional piperazine side chains in selected organic synthesis routes.
Fine chemical synthesis: May be evaluated in the preparation of specialty compounds and functionalized piperazine derivatives.
Pharmaceutical intermediate: Used as a piperazine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.
Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving hydroxyethyl or N-methyl piperazine structures.
Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects involving alcohol derivatization or piperazine ring functionalization.
Related Heterocycle Intermediates
1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0 belongs to Aure Chemical's piperazine derivatives for API building blocks series within our broader heterocycle derivatives for pharmaceutical intermediates portfolio.
Buyers sourcing hydroxyethyl or N-substituted piperazine derivatives may also review related piperazine intermediates such as 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, 1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3, and 4-Methyl-1-piperazinepropanol CAS 5317-33-9.
For related hydroxyethyl nitrogen heterocycles outside the piperazine series, buyers may also compare 4-(2-Hydroxyethyl)morpholine CAS 622-40-2, 1-(2-Hydroxyethyl)piperidine CAS 3040-44-6, and Aure Chemical’s morpholine derivatives for pharmaceutical intermediates.
Aure Chemical: Your Reliable Sourcing Partner
Specification confirmation: Aure Chemical supports product identity, purity, appearance, and specification review based on the agreed grade and available supplier documentation.
Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.
SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.
Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.
Packaging
25 L HDPE drum
Final packaging, capacity and net weight are confirmed in the quotation and order.


