Aure Chemical: Trusted Source of 4-Pyrrolidinopyridine CAS 2456-81-7
4-Pyrrolidinopyridine is a hypernucleophilic pyridine derivative known for its superior catalytic activity in acylation reactions compared to traditional bases. Its pyrrolidine substituent enhances electron donation to the pyridine ring, making it an effective catalyst in organic transformations.
Frequently utilized as a DMAP alternative in fine chemical synthesis, this compound supports efficient esterification, amidation, and other nucleophilic catalysis processes. Aure Chemical maintains consistent quality for research and process development needs.
Basic Information
| CAS No. | 2456-81-7 |
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| EC No. | 219-534-2 |
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| Linear Formula | C9H12N2 |
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| Molecular Weight | 148.21 |
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| Appearance | White to yellow to orange crystalline solid |
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| Melting Point | 54-58 °C (lit.) |
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| Boiling point | 171-173 °C at 20 mmHg (lit.) |
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| Density | 1.06 g/cm³ (lit., predicted) |
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| Solubility | Soluble in methanol and other polar organic solvents |
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| Storage Conditions | Store at room temperature in a cool, dry place, protected from light and moisture |
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| Chemical Structure |  |
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Key Applications
Organic synthesis intermediate: Serves as a building block and hypernucleophilic catalyst in various acylation and esterification reactions.
Fine chemical intermediate: Applied in the production of specialty chemicals requiring efficient nucleophilic catalysis.
Heterocyclic synthesis: Facilitates construction of complex pyridine and nitrogen-containing heterocyclic frameworks.
Laboratory research: Widely used in medicinal chemistry and method development for catalytic transformations.
Process development: Supports route optimization and scale-up of reactions where enhanced catalytic activity is required.
Aure Chemical: Your Reliable Partner
Consistent product quality: Aure Chemical offers material with high purity and reliable batch consistency suitable for catalytic applications in organic synthesis.
Stable global supply: We provide dependable international logistics and flexible supply options from research quantities to larger scale orders.
SDS and COA support: Detailed safety data sheets and certificates of analysis are available to facilitate quality assurance and regulatory compliance.
Packaging and technical service: Customized packaging in 1 kg to 25 kg sizes with appropriate liners, supported by professional technical communication.