Explore Top-Quality N-Phenyltriflimide (PhNTf2, CAS 37595-74-7) with Aure Chemical
Aure Chemical is a premier global supplier of high-quality N-Phenyltriflimide, commonly abbreviated as PhNTf2. Identified by its CAS number 37595-74-7, N-Phenyltriflimide is a white to off-white crystalline solid highly regarded in organic chemistry for its unique properties as a non-nucleophilic triflating agent and a versatile Lewis acid. Unlike other triflating agents, PhNTf2 offers a milder and more selective approach to introduce the triflate group, minimizing unwanted side reactions. It is an indispensable reagent for creating highly reactive intermediates such as vinyl triflates and enol triflates, crucial for carbon-carbon bond formation reactions. Its applications are vital in the synthesis of complex pharmaceuticals, agrochemicals, natural products, and advanced materials. Aure Chemical is committed to providing N-Phenyltriflimide that meets stringent purity and performance requirements, ensuring consistent and reliable results for your most demanding industrial and research applications. Partner with us for a dependable supply of this critical chemical.
Product Overview & Key Properties
N-Phenyltriflimide (PhNTf2, CAS No. 37595-74-7) is meticulously produced and rigorously tested to meet stringent quality standards. We offer various grades to suit your specific application requirements:
| CAS No.: | 37595-74-7 |
| EC No.: | 609-445-0 |
| Linear Formula: | PhN(SO₂CF₃)₂ |
| Molecular Weight: | 357.25 |
| Appearance: | White to off-white crystalline solid. |
| Melting Point: | 100-102 °C(lit.) |
| Boiling point: | 305.3±52.0 °C(Predicted) |
| Density: | 1.766±0.06 g/cm3(Predicted) |
| Solubility: | Soluble in many common organic solvents (e.g., dichloromethane, THF, toluene, acetonitrile). |
| Stability: | Relatively stable under anhydrous conditions. |
| Purity: | Available in high purity grades (e.g., 98% min) for sensitive synthetic applications. |
| Chemical Structure: |  |
Our commitment to delivering high-purity N-Phenyltriflimide ensures a reliable and efficient component for your critical processes, offering consistent quality for diverse synthetic and industrial applications.
Primary Applications of N-Phenyltriflimide (PhNTf2)
N-Phenyltriflimide's unique properties as a non-nucleophilic triflating agent and mild Lewis acid make it an invaluable reagent with significant applications in various advanced chemical processes:
Triflating Agent / Derivatizing Agent:
PhNTf2 is widely used for introducing the trifluoromethanesulfonyl (triflyl) group ($CF_3SO_2-$) into organic molecules. Its key applications include:
Synthesis of Enol Triflates: Reacts with ketones and aldehydes (often in the presence of a non-nucleophilic base) to form enol triflates, which are highly reactive intermediates for cross-coupling reactions (e.g., Suzuki, Heck) and other C-C bond formations.
Synthesis of Vinyl Triflates: Similarly used to prepare vinyl triflates from enones, useful in palladium-catalyzed couplings.
Activation of Hydroxyl Groups: Converts alcohols into triflates, making them excellent leaving groups for substitution, elimination, and rearrangement reactions, often with high stereoselectivity.
Lewis Acid Catalyst:
It can function as a mild Lewis acid catalyst in various organic reactions where stronger Lewis acids might lead to undesirable side reactions or decomposition. This includes certain types of condensations, additions, and rearrangements.
Non-Nucleophilic Base / Proton Scavenger:
Although primarily a triflating agent, the imide anion formed after triflation is a very weak nucleophile. In some contexts, it can act as a non-nucleophilic base or proton scavenger, particularly when paired with a strong acid.
Pharmaceutical and Agrochemical Synthesis:
PhNTf2 is a crucial reagent in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise and selective functionalization of molecules, which is vital for drug discovery and development.
Natural Product Synthesis:
Its ability to facilitate stereoselective reactions and generate reactive intermediates makes it highly valuable in the total synthesis of intricate natural products.
Why Choose Aure Chemical for Your N-Phenyltriflimide (PhNTf2) Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your N-Phenyltriflimide requirements, you benefit from:
Exceptional Purity & Consistent Quality: Our N-Phenyltriflimide is manufactured to stringent purity specifications, crucial for achieving optimal and reproducible results in sensitive organic syntheses and demanding industrial processes.
Reliable Global Supply Chain: We maintain a robust and efficient global supply network, guaranteeing timely and secure delivery of this essential, reactive chemical to your facilities worldwide, with specialized packaging and handling expertise.
Expert Technical Support: Our dedicated team of specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, optimal storage, and usage in your specific chemical processes, ensuring maximum safety and efficiency.
Commitment to Quality & Responsible Stewardship: We adhere to the highest industry standards for quality management, environmental responsibility, and product stewardship across all our operations, ensuring peace of mind for our clients and sustainable sourcing practices.
Customized Solutions: We understand that different applications may require specific purity levels or formulations. We are open to discussing customized solutions to meet your exact requirements.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality N-Phenyltriflimide (PhNTf2). We're ready to empower your most advanced chemical synthesis and research endeavors with an unwavering commitment to quality and excellence.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
