Shandong Aure Chemical Co., Ltd.

Hexamethyldisilazane (HMDS) CAS 999-97-3

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Hexamethyldisilazane (HMDS) CAS 999-97-3

Synonyms: HMDS; Bis(trimethylsilyl)amine; 1,1,1,3,3,3-Hexamethyldisilazane; Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)- 

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of HMDS in China and also one of the manufacturers of this product.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

Please contact us to obtain the latest product information.

Product Details

Discover Aure Chemical's Premium Hexamethyldisilazane (HMDS) Supply

Aure Chemical is a leading supplier of Hexamethyldisilazane (HMDS), a versatile organosilicon compound crucial for a wide range of industrial and specialty applications. We provide high-purity HMDS, ensuring consistent quality for your demanding processes.


Basic Information of Hexamethyldisilazane

Hexamethyldisilazane (HMDS CAS 999-97-3), also known as bis(trimethylsilyl)amine, is an organic silicon compound with the chemical formula [(CH₃)₃Si]₂NH. It's a clear, colorless liquid with a characteristic ammonia-like odor. Its unique chemical structure, featuring two trimethylsilyl groups bonded to a nitrogen atom, makes it an excellent silylating agent, meaning it can introduce trimethylsilyl groups into other molecules.

CAS No.:999-97-3
EC No.:213-668-5
Linear Formula:[(CH₃)₃Si]₂NH
Molecular Weight:161.39
Appearance:Transparent Liquid
Melting Point:-78 °C
Boiling point:125 °C (lit.)
Density:0.774 g/mL at 25 °C(lit.)
Flash Point:57.2 °F
RIDADR:UN 3286 3, 8, 6.1/PG 2
Chemical Structure:Molecular Structure of Hexamethyldisilazane

Key Features and Benefits

  • High Purity: Our HMDS is manufactured to strict quality standards, ensuring minimal impurities for optimal performance.

  • Excellent Silylating Agent: It efficiently adds trimethylsilyl groups to hydroxyl (-OH), amino (-NH), and thiol (-SH) functionalities, converting them into more volatile or stable derivatives.

  • Effective Water Scavenger: HMDS reacts readily with water, making it an excellent drying agent in moisture-sensitive reactions and processes.

  • Versatile Reactant: Its reactivity allows for its use in various chemical syntheses.


Applications of HMDS

Hexamethyldisilazane (HMDS) plays a critical role across numerous industries due to its diverse properties:

  • Pharmaceutical Synthesis: Widely used as a silylating agent and protecting group in the synthesis of active pharmaceutical ingredients (APIs), including antibiotics and steroids. It helps to enhance solubility, facilitate reactions, and protect sensitive functional groups during complex syntheses.

  • Semiconductor Industry: Crucial as an adhesion promoter in photolithography processes. It treats silicon wafers to improve the adhesion of photoresists, leading to better pattern definition and yield in microchip manufacturing.

  • Gas Chromatography (GC): Employed for derivatization of polar compounds (e.g., alcohols, amines, carboxylic acids) to make them more volatile and thermally stable, enabling their analysis by GC.

  • Rubber and Plastics: Used as a surface modifier to improve the compatibility of inorganic fillers (like silica) with polymer matrices, enhancing the mechanical properties of rubber and plastic products.

  • Silicone Chemistry: Serves as a raw material or intermediate in the production of various silicone compounds and polymers.

  • Hydrophobic Coatings: Utilized to create hydrophobic (water-repellent) surfaces on glass, textiles, and other materials.


Why Choose Aure Chemical for HMDS?

At Aure Chemical, we are committed to providing top-quality chemical products and exceptional customer service. Our HMDS product stands out due to:

  • Reliable Supply: Consistent availability to meet your production demands.

  • Quality Assurance: Rigorous quality control processes ensure product purity and performance.

  • Technical Support: Our knowledgeable team is ready to assist with product information and application guidance.

  • Competitive Pricing: We offer cost-effective solutions without compromising on quality.


Hazards Classification

  • GHS Classification: Flammable Liquid (GHS02), Corrosive (GHS05), Acute Toxicity (GHS06)

  • Hazard Statements: Highly flammable liquid and vapor; causes severe skin burns and eye damage; harmful if swallowed or inhaled.

  • UN Number: UN 3286

  • Hazard Class: 3 (Flammable Liquids), 8 (Corrosive), 6.1 (Toxic)

  • Packing Group: II

GHS02: Flammable pictogram
GHS02: Flammable
GHS05: Corrosive pictogram
GHS05: Corrosive
GHS06: Acute toxicity pictogram
GHS06: Acute toxicity

Packaging, Transportation & Storage

Aure Chemical ensures that all products are handled in compliance with international safety and quality standards. Each product’s SDS should be consulted for detailed requirements.

Packaging

We use certified UN-rated containers suitable for each chemical type — including steel drums, HDPE drums, IBCs, and ISO tank containers for bulk liquids. All packages are tested for integrity and labeled per IMDG / IATA / ADR standards.

Transportation

Shipments comply with IMDG, IATA, and ADR codes to ensure safe and lawful movement by sea, air, or land. Accompanying documents include SDS, Dangerous Goods Declarations, and COAs.

Storage

Products should be stored in well-ventilated, dry areas, away from heat and incompatible substances. Follow ISO 9001 / 14001 principles for safety, labeling, and periodic inspection.

For detailed handling or customized packaging inquiries, please    contact us.


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