Aure Chemical is a leading supplier of Hexamethyldisilazane (HMDS), a versatile organosilicon compound crucial for a wide range of industrial and specialty applications. We provide high-purity HMDS, ensuring consistent quality for your demanding processes.
What is Hexamethyldisilazane (HMDS)?
Hexamethyldisilazane (HMDS), also known as bis(trimethylsilyl)amine, is an organic silicon compound with the chemical formula [(CH₃)₃Si]₂NH. It's a clear, colorless liquid with a characteristic ammonia-like odor. Its unique chemical structure, featuring two trimethylsilyl groups bonded to a nitrogen atom, makes it an excellent silylating agent, meaning it can introduce trimethylsilyl groups into other molecules.
Basic Information of HMDS
| CAS No.: | 999-97-3 |
| EC No.: | 213-668-5 |
| Linear Formula: | [(CH₃)₃Si]₂NH |
| Molecular Weight: | 161.39 |
| Appearance: | Transparent Liquid |
| Melting Point: | -78 °C |
| Boiling point: | 125 °C (lit.) |
| Density: | 0.774 g/mL at 25 °C(lit.) |
| Solubility: | Miscible with acetone, benzene, ethyl ether, heptane and perchloroethylene |
| Flash Point: | 57.2 °F |
| RIDADR: | UN 3286 3/PG 2 |
| Chemical Structure: |  |
Key Features and Benefits
High Purity: Our HMDS is manufactured to strict quality standards, ensuring minimal impurities for optimal performance.
Excellent Silylating Agent: It efficiently adds trimethylsilyl groups to hydroxyl (-OH), amino (-NH), and thiol (-SH) functionalities, converting them into more volatile or stable derivatives.
Effective Water Scavenger: HMDS reacts readily with water, making it an excellent drying agent in moisture-sensitive reactions and processes.
Versatile Reactant: Its reactivity allows for its use in various chemical syntheses.
Applications of HMDS
Hexamethyldisilazane (HMDS) plays a critical role across numerous industries due to its diverse properties:
Pharmaceutical Synthesis: Widely used as a silylating agent and protecting group in the synthesis of active pharmaceutical ingredients (APIs), including antibiotics and steroids. It helps to enhance solubility, facilitate reactions, and protect sensitive functional groups during complex syntheses.
Semiconductor Industry: Crucial as an adhesion promoter in photolithography processes. It treats silicon wafers to improve the adhesion of photoresists, leading to better pattern definition and yield in microchip manufacturing.
Gas Chromatography (GC): Employed for derivatization of polar compounds (e.g., alcohols, amines, carboxylic acids) to make them more volatile and thermally stable, enabling their analysis by GC.
Rubber and Plastics: Used as a surface modifier to improve the compatibility of inorganic fillers (like silica) with polymer matrices, enhancing the mechanical properties of rubber and plastic products.
Silicone Chemistry: Serves as a raw material or intermediate in the production of various silicone compounds and polymers.
Hydrophobic Coatings: Utilized to create hydrophobic (water-repellent) surfaces on glass, textiles, and other materials.
Why Choose Aure Chemical for HMDS?
At Aure Chemical, we are committed to providing top-quality chemical products and exceptional customer service. Our HMDS product stands out due to:
Reliable Supply: Consistent availability to meet your production demands.
Quality Assurance: Rigorous quality control processes ensure product purity and performance.
Technical Support: Our knowledgeable team is ready to assist with product information and application guidance.
Competitive Pricing: We offer cost-effective solutions without compromising on quality.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
