Aure Chemical: Your Trusted Source for High-Purity 4-Aminopyridine (CAS 504-24-5)
Aure Chemical is a leading global supplier of high-purity 4-Aminopyridine, also systematically known as Pyridin-4-amine or commonly as γ-Aminopyridine. This crucial pyridine derivative holds significant importance due to its unique biological activity and versatile chemical properties, driven by the amino group positioned para (opposite) to the nitrogen atom on the pyridine ring. Our 4-Aminopyridine is an indispensable component, primarily serving as a key active pharmaceutical ingredient and a vital tool in advanced scientific research, particularly in neuroscience and pharmacology.
Basic Information of 4-Aminopyridine
4-Aminopyridine (CAS No. 504-24-5) is meticulously produced and rigorously tested to meet stringent quality standards. We ensure exceptional purity and consistent performance, essential for your most demanding applications:
| CAS No.: | 504-24-5 |
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| EC No.: | 207-987-9 |
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| Linear Formula: | H₂N–C₅H₄N |
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| Molecular Weight: | 94.11 |
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| Appearance: | White to off-white crystalline powder. |
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| Odor: | Faint, characteristic odor. |
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| Melting point: | 155-158 °C (lit.) |
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| Boiling point: | 273 °C (lit.) |
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| Density: | 1.26 |
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| Solubility: | Soluble in water, ethanol, chloroform, and moderately soluble in benzene and ether. |
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| Flash point: | 156°C |
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| Nature: | Combustible, highly toxic by ingestion, inhalation, and skin absorption. |
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| RIDADR: | UN 2671 6.1/PG 2 |
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| Chemical Structure: |  |
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Our commitment to delivering high-purity 4-Aminopyridine ensures a reliable and efficient component for your critical pharmaceutical and research endeavors.
Primary Applications of 4-Aminopyridine (γ-Aminopyridine)
4-Aminopyridine's distinct pharmacological action and chemical versatility make it an incredibly valuable compound, particularly in the fields of medicine and research:
Pharmaceutical Applications (Fampridine):
4-Aminopyridine is the active pharmaceutical ingredient (API) in Fampridine (marketed as Ampyra in the US and Fampyra in Europe). This medication is specifically approved to improve walking ability in adults with multiple sclerosis (MS). It functions as a potassium channel blocker, which helps to improve nerve conduction in demyelinated axons.
Neuroscience and Electrophysiology Research:
Due to its action as a potassium channel blocker, 4-Aminopyridine is an invaluable tool in neuroscience research. It's used in electrophysiological studies to investigate ion channel function, neuronal excitability, and synaptic transmission, aiding in understanding various neurological disorders.
Chemical Intermediate:
As a reactive aminopyridine, it serves as a building block in the synthesis of other specialty chemicals, including other pyridine derivatives and complex heterocyclic compounds for various applications.
Veterinary Medicine:
In some veterinary applications, it has been used as a central nervous system stimulant, for example, to treat poisoning from certain toxins, though its use requires careful control due to its toxicity.
Why Choose Aure Chemical for Your 4-Aminopyridine Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your 4-Aminopyridine requirements, you benefit from:
Exceptional Purity & Pharmaceutical Grade: Our 4-Aminopyridine is manufactured to meet the highest purity standards, critical for its use in pharmaceutical applications and sensitive scientific research, ensuring reliable and consistent results.
Reliable Global Supply Chain: We maintain a robust and efficient supply network, guaranteeing timely and secure delivery of this essential compound to your facilities worldwide, adhering to all strict safety and regulatory standards for highly toxic materials.
Expert Technical Support: Our team of experienced chemists and specialists is readily available to offer comprehensive guidance on product specifications, safe handling procedures, and optimal storage conditions for 4-Aminopyridine.
Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients handling this potent and toxic material.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality **4-Aminopyridine**. We are ready to support your groundbreaking pharmaceutical development and scientific research.
Hazards Classification
GHS Classification: Acute Toxicity, Oral (GHS06), Acute Toxicity, Dermal (GHS06), Acute Toxicity, Inhalation (GHS06), Skin Irritation (GHS07), Eye Irritation (GHS07)
Hazard Statements: Toxic if swallowed, in contact with skin, or inhaled; causes skin irritation; causes serious eye irritation.
UN Number: UN 2671
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
GHS06: Acute toxicity
GHS07: Skin and eye irritation
