Shandong Aure Chemical Co., Ltd.

1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3

Persistent supply for specialized needs
1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3
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1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3

Synonyms: 1,4-Piperazinediethanol; N,N'-Bis(2-hydroxyethyl)piperazine; 2,2'-(Piperazine-1,4-diyl)diethanol; Piperazine-1,4-bisethanol; 1,4-Di(2-hydroxyethyl)piperazine; N,N'-Di(2-hydroxyethyl)piperazine

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of 1,4-Bis(2-hydroxyethyl)piperazine in China.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

Please contact us to obtain the latest product information.

Product Details

Aure Chemical Supplies 1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3 for Specialty Synthesis

1,4-Bis(2-hydroxyethyl)piperazine is a bis-hydroxyethyl substituted piperazine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure contains a piperazine ring with hydroxyethyl groups attached to both nitrogen atoms, providing diol functionality and a piperazine-based framework for downstream transformation.

This compound may be evaluated when a bis-hydroxyethyl piperazine structure or diol-functional piperazine intermediate is required in organic synthesis. Aure Chemical supports specification confirmation, documentation review, and sourcing feasibility evaluation based on the agreed product grade, supplier batch, quantity, and destination market.


Basic Information

CAS No.122-96-3
EC No.204-586-0
Linear FormulaC8H18N2O2
Molecular Weight174.24
AppearanceWhite to off-white crystalline solid
Melting Point133-136 °C (lit.)
Boiling point215-220 °C at 50 mm Hg (lit.)
Density1.097 g/cm³ (lit.)
SolubilitySoluble in water and polar organic solvents
Storage ConditionsKeep in a cool, dry place, sealed tightly, protected from light and moisture
Chemical StructureMolecular Structure of 1,4-Bis(2-hydroxyethyl)piperazine

Key Applications

  • Organic synthesis intermediate: Can be used as a bis-hydroxyethyl piperazine intermediate in selected esterification, etherification, coupling, or derivatization routes involving the hydroxyethyl groups.

  • Fine chemical synthesis: May be evaluated in the preparation of specialty chemicals, functionalized piperazine derivatives, and diol-containing organic intermediates.

  • Pharmaceutical intermediate: Used as a piperazine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

  • Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving bis-hydroxyethyl piperazine structures.

  • Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects involving diol functionality, alcohol derivatization, or piperazine ring modification.


Related Heterocycle Intermediates

1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3 belongs to Aure Chemical's piperazine derivatives for API building blocks series within our broader heterocycle derivatives for pharmaceutical intermediates portfolio.

Buyers sourcing hydroxyethyl or bis-hydroxyethyl piperazine derivatives may also review related piperazine intermediates such as 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, 1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0, and 4-Methyl-1-piperazinepropanol CAS 5317-33-9.

For related hydroxyethyl or hydroxyalkyl nitrogen heterocycles outside the piperazine series, buyers may also compare 4-(2-Hydroxyethyl)morpholine CAS 622-40-2, 1-(2-Hydroxyethyl)piperidine CAS 3040-44-6, and Aure Chemical’s morpholine derivatives for pharmaceutical intermediates.


Aure Chemical: Your Reliable Sourcing Partner

  • Specification confirmation: Aure Chemical supports product identity, purity, appearance, and specification review based on the agreed grade and available supplier documentation.

  • Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.

  • SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

  • Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.

Packaging, Logistics & Compliance Capabilities

Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.

Packaging Options

  • 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
  • 100 kg / 200 kg steel or HDPE drums
  • 500 kg / 1000 kg IBC containers
  • Bulk liquids in ISO tank containers
  • Customized packaging upon request

Transportation Modes

  • Sea freight (FCL / LCL)
  • Air freight for selected products
  • Road and rail transportation
  • Dangerous & non-dangerous cargo handling
  • Incoterms: EXW, FOB, CFR, CIF, DAP, DDP

Storage & Handling

  • Dry, cool, and well-ventilated warehouses
  • Segregation by hazard class
  • FIFO inventory management
  • Temperature-controlled storage if required
  • Regular inspection & labeling control

Documentation & Compliance

  • Safety Data Sheet (SDS)
  • Certificate of Analysis (COA)
  • Dangerous Goods Declaration (DGD)
  • Packing List & Commercial Invoice
  • IMDG / IATA / ADR compliant labeling

For packaging customization or logistics consultation, please contact us.


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