Shandong Aure Chemical Co., Ltd.

1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3

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1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3
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1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3

Synonyms: 1,4-Piperazinediethanol; N,N'-Bis(2-hydroxyethyl)piperazine; 2,2'-(Piperazine-1,4-diyl)diethanol; Piperazine-1,4-bisethanol; 1,4-Di(2-hydroxyethyl)piperazine; N,N'-Di(2-hydroxyethyl)piperazine

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of 1,4-Bis(2-hydroxyethyl)piperazine in China.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

Please contact us to obtain the latest product information.

Product Details

Aure Chemical: Trusted Source of 1,4-Bis(2-hydroxyethyl)piperazine CAS 122-96-3

1,4-Bis(2-hydroxyethyl)piperazine is a symmetric piperazine derivative with hydroxyethyl groups attached to both nitrogen atoms. This diol structure enables participation in esterification, etherification, and polymerization-type reactions while retaining the piperazine core for further derivatization.

It functions as a useful intermediate for introducing hydroxyethylpiperazine units in fine chemical and pharmaceutical routes. Aure Chemical ensures batch consistency appropriate for laboratory research and scale-up activities.


Basic Information

CAS No.122-96-3
EC No.204-586-0
Linear FormulaC8H18N2O2
Molecular Weight174.24
AppearanceWhite to off-white crystalline solid
Melting Point133-136 °C (lit.)
Boiling point215-220 °C at 50 mm Hg (lit.)
Density1.097 g/cm³ (lit.)
SolubilitySoluble in water and polar organic solvents
Storage ConditionsKeep in a cool, dry place, sealed tightly, protected from light and moisture
Chemical StructureMolecular Structure of 1,4-Bis(2-hydroxyethyl)piperazine

Key Applications

  • Organic synthesis intermediate: Serves as a diol building block for esterification and etherification reactions involving the hydroxyethyl groups.

  • Fine chemical intermediate: Used in the preparation of specialty chemicals and functionalized piperazine derivatives.

  • Pharmaceutical intermediate: Applied as a precursor in the synthesis of pharmaceutical compounds requiring hydroxyethylpiperazine side chains.

  • Laboratory research: Employed in medicinal chemistry for exploring new molecular entities and solubility-enhancing modifications.

  • Process development: Supports route optimization involving diol-based coupling or derivatization steps.


Aure Chemical: Your Reliable Partner

  • Consistent product quality: Aure Chemical supplies material with high purity specifications and reliable batch-to-batch consistency for organic intermediate applications.

  • Stable global supply: Established logistics channels support consistent delivery across laboratory, pilot, and production-scale orders.

  • SDS and COA support: Safety data sheets and certificates of analysis are provided upon request to facilitate quality review and compliance.

  • Packaging and technical service: Flexible packaging options from 1 kg to 25 kg with inner liners, complemented by responsive technical assistance.

Packaging, Logistics & Compliance Capabilities

Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.

Packaging Options

  • 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
  • 100 kg / 200 kg steel or HDPE drums
  • 500 kg / 1000 kg IBC containers
  • Bulk liquids in ISO tank containers
  • Customized packaging upon request

Transportation Modes

  • Sea freight (FCL / LCL)
  • Air freight for selected products
  • Road and rail transportation
  • Dangerous & non-dangerous cargo handling
  • Incoterms: EXW, FOB, CFR, CIF, DAP, DDP

Storage & Handling

  • Dry, cool, and well-ventilated warehouses
  • Segregation by hazard class
  • FIFO inventory management
  • Temperature-controlled storage if required
  • Regular inspection & labeling control

Documentation & Compliance

  • Safety Data Sheet (SDS)
  • Certificate of Analysis (COA)
  • Dangerous Goods Declaration (DGD)
  • Packing List & Commercial Invoice
  • IMDG / IATA / ADR compliant labeling

For packaging customization or logistics consultation, please contact us.


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