Aure Chemical: Your Reliable Source for High-Purity Tosyl Chloride (CAS 98-59-9)
Aure Chemical is a premier global supplier of high-quality Tosyl Chloride (TsCl), systematically named p-Toluenesulfonyl chloride. Identified by its CAS number 98-59-9, this organic compound is a white, crystalline solid known for its sharp, distinctive odor. Tosyl Chloride is a remarkably versatile and indispensable reagent in organic synthesis. Its primary utility lies in its ability to activate hydroxyl groups (converting alcohols into excellent leaving groups, tosylates), serve as a protecting group for alcohols and amines, and act as a sulfonating agent. These diverse functions make it a cornerstone in the manufacturing of pharmaceuticals, agrochemicals, dyes, and various other specialty chemicals. Aure Chemical's unwavering commitment to excellence ensures that our Tosyl Chloride meets the stringent purity and performance requirements for your most demanding industrial and laboratory applications, guaranteeing consistency, reliability, and superior results.
Product Overview & Key Properties
Tosyl Chloride (CAS No. 98-59-9) is meticulously produced and rigorously tested to meet stringent quality standards. We ensure exceptional purity and consistent performance, essential for your critical applications:
| CAS No.: | 98-59-9 |
| EC No.: | 202-684-8 |
| Linear Formula: | CH₃C₆H₄SO₂Cl |
| Molecular Weight: | 190.65 |
| Appearance: | White crystalline solid. |
| Melting Point: | 65-69 °C(lit.) |
| Boiling point | 134 °C10 mm Hg(lit.) |
| Density: | 1,006 g/cm3 |
| Solubility: | Insoluble in water (reacts slowly). Soluble in common organic solvents like ether, benzene, acetone, and hot alcohol. |
| Reactivity: | Reacts with water, alcohols, amines, and other nucleophiles. Stable under dry conditions. |
| Storage: | Should be stored in a cool, dry place, protected from moisture. |
| RIDADR: | UN 3261 8/PG 2 |
| Chemical Structure: |  |
Our commitment to delivering high-purity Tosyl Chloride ensures a reliable and efficient component for your critical processes, offering consistent quality for diverse industrial needs, while prioritizing uncompromising safety in handling and storage.
Primary Applications of Tosyl Chloride
Tosyl Chloride's unique versatility makes it an indispensable reagent in a broad range of organic synthesis applications across various industries:
Activation of Alcohols:
One of its most significant applications is in the activation of alcohols. It converts a hydroxyl group (-OH), which is a poor leaving group, into a good leaving group (a tosylate, -OTs). This transformation facilitates subsequent nucleophilic substitution reactions to form alkyl halides, amines, nitriles, and other functional groups.
Protecting Group for Alcohols and Amines:
It is widely used as a protecting group in multi-step organic syntheses. Alcohols can be converted to tosylates to protect them during reactions involving other parts of the molecule. Similarly, primary and secondary amines can be protected as sulfonamides.
Synthesis of Sulfonates and Sulfonamides:
Tosyl Chloride is a key reagent for synthesizing various sulfonates (esters of sulfonic acids) and sulfonamides by reacting with alcohols and amines, respectively. These derivatives have various industrial applications, including pharmaceuticals and surfactants.
Pharmaceutical Manufacturing:
It is a crucial intermediate and reagent in the synthesis of numerous active pharmaceutical ingredients (APIs) and their precursors. Its role in activating hydroxyl groups and forming sulfonamides is vital for creating specific molecular structures in drug development.
Dye and Pigment Industry:
Used in the production of certain dyes and pigments, where the introduction of the tosyl group or subsequent reactions play a role in their chemical structure and properties.
Other Specialty Chemical Synthesis:
Plays a role in the synthesis of various specialty chemicals, including certain types of polymers, catalysts, and additives, where its electrophilic nature and ability to form good leaving groups are leveraged.
Why Choose Aure Chemical for Your Tosyl Chloride Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your Tosyl Chloride requirements, you benefit from:
Exceptional Purity & Consistent Quality: Our Tosyl Chloride is manufactured to stringent purity specifications, crucial for optimizing performance and yield in sensitive organic synthesis reactions, particularly in pharmaceutical and fine chemical production.
Reliable Global Supply Chain: We maintain a robust and efficient global supply network, guaranteeing timely and secure delivery of this essential reagent to your facilities worldwide, adhering to all strict safety and regulatory standards.
Expert Technical Support: Our dedicated team of experienced chemists and specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, and optimal storage conditions for Tosyl Chloride.
Commitment to Quality & Responsible Stewardship: We adhere to the highest industry standards for quality management, environmental responsibility, and product stewardship across all our operations, ensuring peace of mind for our clients.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality Tosyl Chloride. We're ready to support your most demanding and innovative chemical processes with an unwavering commitment to quality and excellence.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
