methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate CAS 1181267-30-0

Name: methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate CAS 1181267-30-0
Brand: Aure Chemical
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Synonyms: methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate; Bilastine ITS-2; Bilastine intermediate; 2-methyl-2-{4-[2-(toluene-4-sulfonyloxy)ethyl]phenyl}propanoic acid methyl ester; methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate; Bilastine Impurity 22; Bilastine impurity N19; Methyl-2-methyl-2-(4-2-p-toluenesulfonyloxyethylphenyl isopropyl ester;

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Product Details

Aure Chemical Supplies Premium methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate CAS 1181267-30-0 for Global Industries

This tosylate-protected intermediate enables controlled alkylation steps in complex molecule assembly. Aure Chemical delivers material with specifications aligned to pharmaceutical synthesis requirements and full traceability.

Basic Information

CAS No.	1181267-30-0
EC No.	Not available
Linear Formula	C20H24O5S
Molecular Weight	376.47
Appearance	Off-white to pale yellow solid or viscous liquid
Melting Point	Not available (typical reference)
Boiling point	505 ± 38 °C (predicted, lit.)
Density	1.184 ± 0.06 g/mL (predicted, lit.)
Solubility	Soluble in organic solvents such as dichloromethane, ethyl acetate, and methanol; insoluble in water
Storage Conditions	Sealed in dry container at room temperature, protected from moisture and light
Chemical Structure

Key Applications

Pharmaceutical intermediate: An essential building block in the multi-step synthesis of bilastine, a non-sedating antihistamine API, and an important component within Bilastine and specialty antihistamine intermediates for pharmaceutical development.
API intermediate: Introduces the functionalized phenethyl side chain required for bilastine core structure assembly in advanced antihistamine synthesis.
Organic synthesis intermediate: Provides a reactive tosylate group for nucleophilic substitution in aromatic propanoate derivatives used in pharmaceutical and fine chemical synthesis.
Laboratory research: Employed in exploratory synthesis and analog preparation for antihistamine and related therapeutic compounds, especially in the development of specialty antihistamine intermediates.
Process development: Facilitates route scouting and optimization for scalable production of high-purity bilastine intermediates and pharmaceutical intermediates for API synthesis.

Aure Chemical: Your Reliable Partner

Consistent product quality: Rigorous analytical verification ensures high purity and reproducible characteristics for demanding synthetic applications.
Stable global supply: Secure procurement and logistics channels provide uninterrupted availability for research through commercial volumes.
SDS and COA support: Complete documentation packages including SDS and COA delivered promptly to support quality and regulatory needs.
Packaging and technical service: Tailored packaging in 1kg to 25kg fiber drums or cartons with inner liners, along with dedicated technical consultation.