Shandong Aure Chemical Co., Ltd.

Bis(2-chloroethyl)amine hydrochloride CAS 821-48-7

Persistent supply for specialized needs
Bis(2-chloroethyl)amine hydrochloride CAS 821-48-7
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Bis(2-chloroethyl)amine hydrochloride CAS 821-48-7

Synonyms: Bis(2-chloroethyl)amine hydrochloride; 2,2'-Dichlorodiethylamine hydrochloride; β,β′-Dichlorodiethylamine hydrochloride; 1,5-Dichloro-3-azapentane hydrochloride; N,N-Bis(2-chloroethyl)amine hydrochloride; Nornitrogen mustard hydrochloride; Bis(β-chloroethyl)amine hydrochloride; Di(2-chloroethyl)amine hydrochloride; 2-Chloro-N-(2-chloroethyl)ethanamine hydrochloride

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of Bis(2-chloroethyl)amine hydrochloride in China.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

Please contact us to obtain the latest product information.

Product Details

High-Purity Bis(2-chloroethyl)amine hydrochloride CAS 821-48-7 from Aure Chemical

Bis(2-chloroethyl)amine hydrochloride serves as a reliable organic intermediate in fine chemical manufacturing and pharmaceutical development. The hydrochloride salt form provides improved stability and ease of handling during synthetic operations.

It functions effectively in alkylation reactions to build complex nitrogen-containing structures. Aure Chemical maintains consistent quality standards suitable for research and process applications.


Basic Information

CAS No.821-48-7
EC No.212-479-5
Linear Formula(ClCH₂CH₂)₂NH·HCl
Molecular Weight178.49
AppearanceWhite to off-white crystalline powder
Melting Point212-214 °C (lit.)
Boiling pointNot available (typical reference)
DensityNot available (typical reference)
SolubilitySoluble in water (>100 g/L)
Storage ConditionsStore below +30°C in a cool, dry, well-ventilated place. Keep container tightly closed. Hygroscopic.
Chemical StructureMolecular Structure of Bis(2-chloroethyl)amine hydrochloride

Key Applications

  • Pharmaceutical intermediate: Serves as a building block in the synthesis of active pharmaceutical ingredients including cyclophosphamide and aripiprazole.

  • Organic synthesis intermediate: Used for the preparation of piperazine derivatives and other nitrogen heterocycles via controlled alkylation reactions.

  • Fine chemical intermediate: Enables construction of functional molecules required in specialty chemical production.

  • Laboratory research: Supports exploratory studies in medicinal chemistry and synthetic route scouting.

  • Process development: Facilitates scale-up and optimization of synthetic pathways in pharmaceutical manufacturing.


Advantages of Sourcing from Aure Chemical

  • Consistent product quality: High-purity specifications maintained with routine analytical verification and batch consistency checks.

  • Stable global supply: Established logistics networks ensure reliable delivery for laboratory, pilot, and commercial quantities.

  • SDS and COA support: Full product documentation including SDS and COA provided promptly for compliance and quality review.

  • Packaging and technical service: Flexible options including 1 kg/5 kg/25 kg fiber drums with double PE liners or cartons with inner bags, plus responsive technical assistance.

Packaging, Logistics & Compliance Capabilities

Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.

Packaging Options

  • 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
  • 100 kg / 200 kg steel or HDPE drums
  • 500 kg / 1000 kg IBC containers
  • Bulk liquids in ISO tank containers
  • Customized packaging upon request

Transportation Modes

  • Sea freight (FCL / LCL)
  • Air freight for selected products
  • Road and rail transportation
  • Dangerous & non-dangerous cargo handling
  • Incoterms: EXW, FOB, CFR, CIF, DAP, DDP

Storage & Handling

  • Dry, cool, and well-ventilated warehouses
  • Segregation by hazard class
  • FIFO inventory management
  • Temperature-controlled storage if required
  • Regular inspection & labeling control

Documentation & Compliance

  • Safety Data Sheet (SDS)
  • Certificate of Analysis (COA)
  • Dangerous Goods Declaration (DGD)
  • Packing List & Commercial Invoice
  • IMDG / IATA / ADR compliant labeling

For packaging customization or logistics consultation, please contact us.


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