Bis[2-(2-chloroethoxy)ethyl] Ether CAS 638-56-2

Aure Chemical: Reliable Supplier of Bis[2-(2-chloroethoxy)ethyl] Ether CAS 638-56-2

Bis[2-(2-chloroethoxy)ethyl] ether (CAS 638-56-2), also known as tetraethylene glycol dichloride or 1,11-dichloro-3,6,9-trioxaundecane, is a bifunctional dichloro-terminated polyether derivative featuring two reactive chloroethyl end groups connected by a triethylene glycol chain. This structure makes it a versatile building block for nucleophilic substitution reactions in fine chemical synthesis.

Aure Chemical supplies this specialty dichloro PEG derivative to support global customers engaged in organic synthesis, pharmaceutical intermediate development, and custom synthesis projects. We provide consistent quality coordination and comprehensive documentation to facilitate efficient international sourcing and export.

Basic Information

CAS No.	638-56-2
EC No.	Not available
Linear Formula	C8H16Cl2O3
Molecular Weight	231.12 g/mol
Appearance	Colorless to yellow to green clear liquid
Melting Point	Not available (typical reference)
Boiling point	139 °C at 3 mmHg (lit.)
Density	1.18 g/mL at 20 °C (lit.)
Solubility	Soluble in chloroform and dichloromethane; slightly soluble in ethyl acetate, methanol, and water
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture and incompatible materials. Store at room temperature.
Chemical Structure

Key Applications

• Organic synthesis intermediate: Serves as a bifunctional building block for introducing PEG chains through nucleophilic substitution of the terminal chloro groups in fine chemical and specialty synthesis.

• Molecular linker intermediate: Functions as a precursor for symmetric PEG-based linkers and spacers in the construction of functional molecules and advanced intermediates.

• Fine chemical intermediate: Employed in the preparation of PEGylated specialty compounds and derivatives for pharmaceutical and research applications requiring dichloro-terminated polyethers.

• Laboratory research: Applied in medicinal chemistry studies and synthetic methodology development involving reactive chloroethyl PEG derivatives for further functionalization.

• Custom synthesis: Supports route optimization and custom projects requiring dichloro PEG intermediates for the development of novel PEGylated structures and process intermediates.

Sourcing Bis[2-(2-chloroethoxy)ethyl] Ether with Aure Chemical

• Consistent product quality: High-purity specifications with reliable batch consistency suitable for demanding organic synthesis and fine chemical applications.

• Flexible global supply: Support for laboratory-scale samples, pilot quantities, and bulk orders through established international logistics and export channels.

• SDS and COA support: Comprehensive documentation including Safety Data Sheets and Certificates of Analysis provided to meet quality review and procurement requirements.

• Packaging and technical service: Customized liquid packaging options together with responsive technical communication for sourcing specifications and order coordination.

Packaging and Storage

• Packaging: Supplied in small laboratory quantities and larger liquid containers such as HDPE drums. Customized packaging configurations available upon request for specific volumes and requirements.

• Storage: Store in tightly closed containers in a cool, dry, and well-ventilated area. Recommended storage temperature is room temperature, protected from moisture and light.

• Handling of opened containers: Minimize exposure to air and moisture after opening. Reseal containers tightly and use contents promptly to maintain product integrity.

• Bulk supply: Flexible arrangements supported for pilot-scale and commercial bulk procurement with suitable liquid packaging matched to order quantity.

Safety and Handling

• General handling: Handle in accordance with good laboratory and industrial hygiene practices. Avoid inhalation, ingestion, and direct contact with skin or eyes.

• Personal protection: Wear suitable protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in the work area.

• Documentation review: Always review the latest Safety Data Sheet (SDS) prior to handling, storage, transportation, or use of the product.

• Compatibility: Incompatible with strong oxidizing agents, strong bases, and strong nucleophiles. Conduct compatibility assessment before combining with other materials.