3-Fluoro-4-Aminophenol CAS 399-95-1

High-Purity 3-Fluoro-4-Aminophenol CAS 399-95-1 from Aure Chemical: Stable Supply & Documentation Support

3-Fluoro-4-aminophenol is an aminophenol derivative featuring ortho-fluoro substitution relative to the amino group. This arrangement supports regioselective reactions in aromatic substitution and condensation processes.

It serves mainly as a building block in fine chemical and intermediate synthesis under controlled conditions. Aure Chemical ensures specifications appropriate for pharmaceutical and related applications.

Basic Information

CAS No.	399-95-1
EC No.	402-230-0
Linear Formula	C6H6FNO
Molecular Weight	127.12
Appearance	Light yellow to brown powder or crystals
Melting Point	162 °C (lit.)
Boiling point	Not available (typical reference)
Density	Not available (typical reference)
Solubility	Soluble in organic solvents like methanol, DMSO; limited in water (typical reference)
Storage Conditions	Store in a cool, dark place, sealed, 2-8°C, protect from light
Chemical Structure

Key Applications

• Pharmaceutical intermediate: A key precursor for synthesizing various active pharmaceutical ingredients requiring fluoro-substituted aromatic amines, including intermediates relevant to Gefitinib, Sunitinib and Sorafenib intermediates in targeted therapy development.

• Agrochemical intermediate: Used in the production of insecticides such as flufenoxuron through further functionalization, while also serving as a versatile fluorinated aromatic building block in fine chemical synthesis.

• Aromatic compound synthesis: Enables construction of substituted aniline and phenol derivatives in multi-step organic pathways, making it relevant to fluorinated pharmaceutical intermediates and related medicinal chemistry programs.

• Laboratory research: Applied in medicinal chemistry explorations for novel fluorinated compounds, especially within oncology drug intermediates and other bioactive small-molecule discovery projects.

• Process development: Utilized in route optimization and scale-up for efficient intermediate manufacturing and pharmaceutical intermediates for API synthesis.

Aure Chemical: Your Reliable Partner

• Reliable material quality: Consistent purity and batch uniformity supported by routine analytical testing for intermediate-grade applications.

• Global supply reliability: Established export channels providing stable delivery for lab to pilot quantities worldwide.

• Documentation availability: SDS, COA, and supplementary certificates offered to support quality review and regulatory compliance.

• Technical support and packaging: Responsive assistance for inquiries alongside flexible options like 1kg/5kg/25kg fiber drums with PE liners or custom packaging.