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3-Chloropropionyl Chloride CAS 625-36-5

Synonyms: 3-Chloropropanoyl chloride; 3-Chloropropionic acid chloride; β-Chloropropionyl chloride; β-Chloropropanoyl chloride; Propionyl chloride, 3-chloro-; NSC 84180

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of 3-Chloropropionyl Chloride in China and also one of the manufacturers of this product.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

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Product Details

Premium 3-Chloropropionyl Chloride (CAS 625-36-5) Solutions by Aure Chemical

Aure Chemical is a leading global supplier of 3-Chloropropionyl Chloride, also systematically known as 3-Chloropropanoyl Chloride or β-Chloropropionyl Chloride. This highly reactive and versatile acid chloride is an indispensable building block in advanced organic synthesis. Its unique dual functionality—featuring a highly reactive acyl chloride group and a strategically positioned chlorine atom—makes it a pivotal intermediate for introducing specific functionalities into complex molecules across the pharmaceutical, agrochemical, and specialty chemical industries.


Product Overview & Key Properties

3-Chloropropionyl Chloride (CAS No. 625-36-5) is meticulously manufactured to meet stringent quality standards, ensuring exceptional purity and consistent performance for your demanding applications:

CAS No.:625-36-5
EC No.:210-890-4
Linear Formula: ClCH₂CH₂COCl
Molecular Weight:126.97
Appearance:Clear, colorless to pale yellow liquid.
Odor:Pungent, irritating odor.
Melting Point:-32 °C
Boiling point143-145 °C(lit.)
Density:1.33 g/mL at 25 °C(lit.)
Solubility:Reacts with water; soluble in most common organic solvents like ethers, hydrocarbons, and chlorinated solvents.
Flash Point:146 °F
Nature:Corrosive, moisture-sensitive, highly reactive.
RIDADR:UN 3390 6.1/PG 1
Chemical Structure: cas-625-36-5.jpg

Our commitment to delivering high-purity 3-Chloropropionyl Chloride ensures a reliable and efficient component for your complex chemical syntheses and manufacturing processes.


Primary Applications of 3-Chloropropionyl Chloride

3-Chloropropionyl Chloride's high reactivity and dual functionality make it an invaluable reagent for a wide range of specialized applications:

  1. Pharmaceutical Synthesis:

    It is a vital intermediate in the synthesis of numerous active pharmaceutical ingredients (APIs) and drug precursors. It's used to introduce the 3-chloropropionyl moiety into target molecules via acylation reactions with alcohols, amines, or phenols, which are crucial steps in drug development.

  2. Agrochemical Manufacturing:

    This acid chloride serves as a key building block for the creation of various agrochemicals, including herbicides, insecticides, and fungicides. It allows for the precise incorporation of a chlorinated alkyl chain into biologically active compounds.

  3. Polymer and Resin Synthesis:

    In the polymer industry, it can be used to functionalize monomers or polymers, enabling the introduction of reactive sites or modifying polymer properties for specialized applications.

  4. Specialty Chemicals & Fine Chemicals:

    3-Chloropropionyl Chloride is a versatile intermediate for manufacturing a wide range of specialty chemicals. Its reactivity with nucleophiles makes it suitable for producing esters, amides, and other derivatives used in various industrial processes.

  5. Dyes and Pigments:

    It finds application in the synthesis of specific types of dyes and pigments, where the introduction of a chloropropionyl group contributes to desired color characteristics or improved fastness.


Why Choose Aure Chemical for Your 3-Chloropropionyl Chloride Supply?

Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your 3-Chloropropionyl Chloride requirements, you benefit from:

  • Exceptional Purity & Reactivity: Our 3-Chloropropionyl Chloride is manufactured to exacting purity standards, critical for sensitive synthesis processes, ensuring predictable reaction outcomes and high yields.

  • Reliable Global Supply Chain: We maintain a robust and efficient supply network, guaranteeing timely and secure delivery of this essential chemical to your facilities worldwide, with appropriate packaging for its reactive nature.

  • Expert Technical Support: Our team of experienced chemists and specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, and optimal storage conditions for 3-Chloropropionyl Chloride.

  • Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients.

Choose Aure Chemical for a trustworthy and dependable supply of high-quality 3-Chloropropionyl Chloride. We are ready to support your most complex chemical endeavors.


Packaging, Transportation & Storage Solutions

At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.

I. Packaging SolutionsII. Transportation SolutionsIII. Storage Solutions

We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to:

  • Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids.

  • Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal.

  • Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell.

  • IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions.

  • Lined Bags or Fibre Drums: Primarily used for powdered or granular solids.

  • Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes).

  • Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.

All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions.

We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point.

  • Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage.

  • Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations.

  • Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.

Regardless of the transport mode, we will provide the following essential documentation:

  • Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc.

  • Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities.

  • Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).

Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.

Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles:

  • Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas.

  • Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers).

  • Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors.

  • Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures.

  • Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards.

  • Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs.

  • Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures.

  • Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information.

  • Away from Food and Drinking Water: Avoid cross-contamination.

Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us.

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