Aure Chemical Delivers Reliable 18-Crown-6 (CAS 17455-13-9) at Consistent Quality
18-Crown-6 (CAS 17455-13-9) is a macrocyclic polyether recognized for its selective binding of potassium cations. It serves as an efficient phase-transfer catalyst that enhances the reactivity of potassium salts in non-polar organic solvents during synthetic transformations.
Aure Chemical supplies this specialty reagent in high purity for organic synthesis and fine chemical applications. Our material supports chemists working on coordination chemistry, ion transport studies, and process optimization in laboratory and pilot-scale settings.
Basic Information
| CAS No. | 17455-13-9 |
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| EC No. | 241-473-5 |
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| Linear Formula | C12H24O6 |
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| Molecular Weight | 264.32 |
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| Appearance | White or colorless crystalline solid |
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| Melting Point | 37-40 °C (lit.) |
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| Boiling point | 116 °C at 0.2 mmHg (lit.) |
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| Density | 1.175 g/cm³ (lit.) |
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| Solubility | Soluble in water and common organic solvents (chloroform, acetonitrile, dichloromethane) |
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| Storage Conditions | Store in a tightly closed container in a cool, dry place. Hygroscopic; protect from moisture and light. |
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| Chemical Structure |  |
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Key Applications
Phase-transfer catalysis: 18-Crown-6 is widely used as a highly efficient phase-transfer catalyst, selectively complexing potassium ions (K⁺) to enhance anion reactivity in biphasic systems. It is a core product in Crown Ethers (15-Crown-5 & 18-Crown-6) for Phase Transfer & API Synthesis, where strong cation binding significantly improves reaction rates and yields.
Selective ion complexation: With an optimal cavity size for potassium ions, 18-Crown-6 exhibits excellent selectivity and binding strength, enabling precise ion transport and coordination in both synthetic and analytical systems. This function is central to the crown ether application category.
Fine chemical synthesis: Used in fine chemical production to enhance selectivity and efficiency in potassium-mediated reactions, especially in the synthesis of high-value intermediates and specialty compounds.
Supramolecular and coordination chemistry: Widely applied in research involving host–guest chemistry, supramolecular assemblies, and ion recognition systems, supporting advanced functional material and molecule design.
Process development: Supports route optimization and scale-up by enabling milder reaction conditions, improved selectivity, and efficient ion transport in complex organic processes.
18-Crown-6 belongs to the Crown Ethers for Phase Transfer Catalysis application category and is part of our broader portfolio of Ethers for Pharmaceutical Intermediates & Specialty Synthesis, covering crown ethers, ion-complexing agents, and advanced catalytic systems for API and specialty chemical synthesis.
Aure Chemical: Your Reliable Partner
Consistent product quality: Aure Chemical delivers high-purity 18-Crown-6 with rigorous batch-to-batch consistency verified through dedicated quality control for organic intermediate use.
Flexible global supply: Established logistics networks ensure stable supply from laboratory to bulk scale for international fine chemical customers.
SDS and COA support: Complete SDS, COA, and technical documentation provided upon request to streamline sourcing and regulatory compliance.
Packaging and technical service: Flexible options in 1 kg, 5 kg, and 25 kg fiber drums with PE liners, backed by responsive technical assistance for application support.
