Pentaethylene glycol monomethyl ether CAS 23778-52-1

Aure Chemical Supplies Pentaethylene glycol monomethyl ether CAS 23778-52-1 for PEG Linker and Specialty Synthesis

Pentaethylene glycol monomethyl ether (CAS 23778-52-1), also known as mPEG5-Alcohol or MeO-PEG5-OH, is a monodisperse methoxy-terminated polyethylene glycol derivative featuring a terminal hydroxyl group. This structure makes it a versatile intermediate for further functionalization in organic synthesis and bioconjugation applications.

It is commonly employed in fine chemical and pharmaceutical research as a building block for preparing PEGylated compounds, linkers, and specialty derivatives. Aure Chemical provides reliable sourcing support for this PEG derivative along with essential documentation for global customers.

Basic Information

CAS No.	23778-52-1
EC No.	Not available
Linear Formula	CH₃O(CH₂CH₂O)₄CH₂CH₂OH
Molecular Weight	252.31 g/mol
Appearance	Colorless to light yellow clear liquid
Melting Point	Not available (typical reference)
Boiling point	110 °C at 0.01 Torr (lit.)
Density	1.08 g/cm³
Solubility	Soluble in water and polar organic solvents
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture. Recommended storage at -20°C or 2-8°C.
Chemical Structure

Key Applications

• Methoxy PEG intermediate: Serves as a defined methoxy-terminated PEG5 building block for further derivatization into amines, tosylates, or other functional PEG linkers.

• Fine chemical intermediate: Acts as a versatile reagent for introducing hydrophilic methoxy-PEG segments into complex organic molecules during specialty synthesis.

• Pharmaceutical intermediate: Employed in the preparation of PEGylated drug candidates and intermediates requiring a controlled hydrophilic spacer.

• Process development: Supports laboratory and pilot-scale efforts in optimizing synthetic routes that incorporate precise PEG derivatives.

• Laboratory research: Widely used in medicinal chemistry and bioconjugation research for developing functional PEG linkers and studying structure-property relationships.

Why Work with Aure Chemical for Pentaethylene glycol monomethyl ether

• Consistent product quality: High-purity Pentaethylene glycol monomethyl ether is sourced through established channels with routine quality coordination to meet fine chemical specifications.

• Flexible global supply: We support laboratory, pilot, and bulk procurement needs with stable export logistics and flexible shipping arrangements worldwide.

• SDS and COA support: Comprehensive product documentation including SDS and COA is available upon request to facilitate regulatory review and international procurement.

• Packaging and technical service: Responsive technical communication and assistance with appropriate packaging selection based on order quantity and product characteristics.

Packaging and Storage

• Packaging: Available in small laboratory quantities in sealed containers or sample bottles; larger volumes supplied in suitable HDPE drums. Customized liquid packaging options can be arranged based on specific requirements.

• Storage: Store in a tightly closed container in a cool, dry, well-ventilated place. Protect from moisture. Long-term storage recommended at -20°C or 2-8°C.

• Handling of opened containers: After opening, minimize exposure to air and moisture. Use the contents promptly and reseal the container tightly to maintain product integrity.

Safety and Handling

• General handling: Work in a well-ventilated area or chemical fume hood. Follow standard laboratory practices for handling organic compounds containing ether and alcohol functional groups.

• Personal protection: Wear suitable protective gloves, safety goggles, and protective clothing to prevent skin and eye contact during handling.

• Documentation review: Consult the current Safety Data Sheet (SDS) before handling, storage, or transportation to ensure appropriate precautions are observed.