High-Purity Palladium(II) Acetate from Aure Chemical – Your Trusted Source
Palladium(II) acetate, commonly abbreviated as Pd(OAc)₂ with CAS No. 3375-31-3, is a cornerstone precatalyst in modern palladium-catalyzed organic transformations. Supplied by Aure Chemical as a high-purity reddish-brown powder or crystalline solid, this versatile Pd(II) compound exhibits excellent solubility in organic solvents and serves as an efficient source of Pd(0) or Pd(II) species in numerous reactions. Renowned for its high catalytic activity, broad functional group tolerance, and stability, it plays a pivotal role in carbon-carbon and carbon-heteroatom bond formations essential to pharmaceutical, agrochemical, and fine chemical manufacturing. Aure Chemical delivers consistent purity levels, precise Pd content, and reliable supply to support scalable processes from laboratory discovery to commercial production.
Basic Information of Palladium(II) Acetate
Aure Chemical provides Palladium(II) Acetate as a premium-grade organometallic precatalyst widely used in homogeneous catalysis, available in high-purity solid form with controlled metal content.
| Parameter | Value |
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| CAS No. | 14221-01-3 |
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| EC No. | 238-086-9 |
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| Chemical Formula | C72H60P4Pd |
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| Molecular Weight | 1155.56 g/mol |
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| Appearance | Yellow to light yellow to beige crystalline powder or crystals |
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| Odor | Odorless |
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| Melting point | 103-107 °C (decomposes) |
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| Boiling point | Not applicable (decomposes) |
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| Density | approx. 1.4 g/cm³ |
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| Solubility | Insoluble in water; soluble in benzene, toluene, THF, dichloromethane, chloroform (air-sensitive solutions) |
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| Nature (hazards) | Harmful if swallowed, may cause long lasting harmful effects to aquatic life, air-sensitive |
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| RIDADR | Not regulated (not subject to transport regulations as hazardous material in many classifications) |
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| Chemical Structure | [Insert Molecular Structure Image Here] |
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Aure Chemical offers customizable options including purity grades (e.g., 98%+, trace metals basis), Pd content verification, packaging under inert atmosphere, and tailored batch sizes to suit your synthesis needs.
Primary Applications of Palladium(II) Acetate
Palladium(II) Acetate serves as a highly effective precatalyst or direct catalyst in a wide array of palladium-mediated reactions, driving innovation in synthetic chemistry across industries.
Cross-Coupling Reactions
Acts as a key precursor in Suzuki-Miyaura, Heck, Sonogashira, and Negishi couplings, enabling efficient aryl-aryl, aryl-alkenyl, and aryl-alkynyl bond formations in pharmaceutical and agrochemical intermediates.
C-H Activation and Functionalization
Facilitates direct C-H arylation, acetoxylation, and olefination of arenes and heterocycles, providing atom-economical routes to complex molecules with minimal prefunctionalization.
Carbon-Heteroatom Bond Formation
Supports Buchwald-Hartwig amination and related ether/thioether couplings, delivering high-yield, selective access to nitrogen- and oxygen-linked pharmacophores under mild conditions.
Pharmaceutical API Synthesis
Widely employed in multistep syntheses of active pharmaceutical ingredients, offering excellent selectivity, functional group compatibility, and scalability for commercial production.
Fine Chemicals and Material Science
Enables synthesis of advanced intermediates, ligands, and functional materials, including OLED components, dyes, and polymers through precise Pd-catalyzed transformations.
Research and Catalyst Development
Serves as a standard Pd source for mechanistic studies, ligand screening, and development of novel palladium catalytic systems in academic and industrial R&D.
Why Choose Aure Chemical for Your Palladium(II) Acetate Supply?
Select Aure Chemical as your strategic partner for Palladium(II) Acetate, benefiting from our expertise in precious metal compounds and dedication to quality and reliability.
Exceptional Purity and Reproducibility
Advanced quality controls guarantee consistent Pd content, low impurity profiles, and reliable catalytic performance across batches.
Secure Precious Metal Sourcing
Transparent, responsible procurement of palladium with inventory buffering to ensure supply continuity despite market dynamics.
Technical Application Support
Experienced chemists offer reaction optimization, scale-up guidance, and troubleshooting to enhance your process efficiency.
Comprehensive Regulatory Compliance
Full documentation suite including COA, REACH, RoHS, and detailed SDS to streamline your global operations and audits.
Sustainability Focus
Ethical sourcing practices and precious metal recovery/recycling programs aligned with modern ESG requirements.
Hazards Classification
GHS Classification: Skin Sensitization (Category 1); Serious Eye Damage (Category 1); Aquatic Acute (Category 1); Aquatic Chronic (Category 1)
Hazard Statements: H317: May cause an allergic skin reaction; H318: Causes serious eye damage; H410: Very toxic to aquatic life with long lasting effects
UN Number: UN 3077
Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
GHS07: Exclamation mark (sensitizer, irritant)
GHS05: Corrosive (serious eye damage)
GHS09: Environment (aquatic toxicity)