Aure Chemical: Your Premier Source for High-Purity 4-Picoline (CAS 108-89-4)
Aure Chemical is a leading global supplier of 4-Picoline, commonly known as γ-Picoline or systematically as 4-Methylpyridine. This vital pyridine derivative is a highly sought-after chemical intermediate, renowned for the unique reactivity imparted by its methyl group positioned para (opposite) to the nitrogen atom on the pyridine ring. Our high-purity 4-Picoline is an indispensable building block, primarily serving as the key precursor for life-saving pharmaceuticals like Isoniazid, and also finding significant applications in the synthesis of diverse agrochemicals and other specialty chemicals.
Product Overview & Key Properties
4-Picoline (CAS No. 108-89-4) is meticulously produced and rigorously tested to meet stringent quality standards. We ensure exceptional purity and consistent performance, essential for your most demanding applications:
| CAS No.: | 108-89-4 |
| EC No.: | 203-626-4 |
| Linear Formula: | CH₃–C₅H₄N |
| Molecular Weight: | 93.13 |
| Appearance: | Transparent Liquid |
| Odor: | Distinctive, unpleasant odor. |
| Melting Point: | 2.4 °C (lit.) |
| Boiling point | 145 °C (lit.) |
| Density: | 0.957 g/mL at 25 °C (lit.) |
| Solubility: | Miscible with water, ethanol, ether, and most organic solvents. |
| Flash Point: | 134 °F |
| Nature: | Flammable liquid and vapor, harmful. |
| RIDADR: | UN 1992 3/PG 3 |
| Chemical Structure: |  |
Our commitment to delivering high-purity 4-Picoline ensures a reliable and efficient component for your complex manufacturing and synthesis processes.
Primary Applications of 4-Picoline (γ-Picoline)
4-Picoline's unique structure and reactivity, particularly the activated methyl group, make it an incredibly valuable and versatile chemical intermediate with applications spanning numerous industries:
Pharmaceutical Synthesis (Isoniazid & Vitamin B6 Precursors):
4-Picoline is a critical precursor in the synthesis of Isoniazid, a frontline drug used for the treatment and prevention of tuberculosis. Its oxidation leads to Isonicotinic acid, a key intermediate for Isoniazid. Furthermore, 4-Picoline derivatives are important for synthesizing Vitamin B6 (Pyridoxine) and its related forms.
Agrochemical Manufacturing:
It serves as a key building block in the synthesis of a variety of agrochemicals, including certain herbicides and fungicides. The pyridine ring structure contributes to the biological activity of these crop protection agents.
Specialty Chemicals and Fine Chemicals:
Due to its reactive methyl group, 4-Picoline can undergo various transformations (e.g., oxidation, halogenation, condensation) to yield a diverse array of fine chemicals, including 4-pyridinecarboxylic acid and its derivatives, used in various organic syntheses.
Polymer Additives:
Some derivatives of 4-Picoline can be used as additives in polymer formulations to impart specific properties.
Solvent and Reagent:
While primarily an intermediate, 4-Picoline can also serve as a specialty solvent or as a reagent in specific organic reactions due to its basicity and ability to participate in various chemical transformations.
Why Choose Aure Chemical for Your 4-Picoline Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your 4-Picoline requirements, you benefit from:
Exceptional Purity & Consistency: Our 4-Picoline is manufactured to stringent purity specifications, critical for maximizing yields in complex syntheses like Isoniazid production and ensuring consistent quality in all your downstream products.
Reliable Global Supply Chain: We maintain a robust and efficient supply network, guaranteeing timely and secure delivery of this essential chemical to your facilities worldwide, adhering to all strict safety and regulatory standards for hazardous materials.
Expert Technical Support: Our team of experienced chemists and specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, and optimal storage conditions for 4-Picoline.
Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients handling this versatile material.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality 4-Picoline. We are ready to support your most demanding and innovative chemical manufacturing processes.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
