3,6-Dioxa-1,8-octanedithiol CAS 14970-87-7

Aure Chemical Delivers Reliable 3,6-Dioxa-1,8-octanedithiol (CAS 14970-87-7) at Consistent Quality

3,6-Dioxa-1,8-octanedithiol is a flexible dithiol featuring terminal mercapto groups linked by an ethylene glycol ether backbone. It is valued in specialty chemical and research applications for its relatively low odor compared with many conventional thiols and for its dual functionality as both a reactive intermediate and a scavenger. Aure Chemical supplies this material to support industrial and laboratory users requiring consistent quality for synthesis and formulation work.

Basic Information

CAS No.	14970-87-7
EC No.	239-044-2
Linear Formula	C6H14O2S2
Molecular Weight	182.30
Appearance	Colorless to light yellow to light orange clear liquid
Melting Point	Not available (liquid at room temperature, lit.)
Boiling point	225 °C (lit.)
Density	1.12 g/mL at 25 °C (lit.)
RIDADR	UN 2810 Class 6.1 / PG III
Chemical Structure

Key Applications

• Low-odor scavenger in Fmoc solid-phase peptide synthesis – Widely adopted as a non-malodorous alternative to ethanedithiol for trapping reactive carbocations during TFA cleavage, improving laboratory handling while maintaining peptide purity.

• Monomer for poly(disulfide) synthesis – Serves as a key building block in radical ring-opening redox polymerization (R3P) to produce biodegradable poly(disulfide) materials under mild catalytic conditions.

• Chemical intermediate in organic and pharmaceutical synthesis – Used in the preparation of sulfur-containing intermediates and functional molecules where a flexible dithiol linker is required.

• Surface modification and self-assembled monolayers – Applied in the formation of stable SAMs on gold and other noble-metal surfaces for nanoelectronics and sensor applications due to its hydrophilic ether spacer.

• Model compound and research reagent – Employed as a model for thioredoxin-type active sites and in peptide-related studies, including cleavage processes and metal-coordination investigations.

Aure Chemical: Your Reliable Partner for 3,6-Dioxa-1,8-octanedithiol

• Consistent product quality – Each batch is controlled to meet industrial and research specifications, supporting reproducible performance in synthesis and formulation.

• Stable international supply – Established logistics networks enable reliable bulk and laboratory-scale deliveries to customers worldwide.

• Full documentation support – SDS, COA and transport classification documents are provided to facilitate regulatory and procurement compliance.

• Flexible packaging and technical assistance – Packaging options and responsive technical communication help match specific process and shipment requirements.

Hazards Classification

GHS Classification: Acute toxicity, oral (Category 3) – GHS06; Acute toxicity, inhalation (Category 4) – GHS07; Skin irritation (Category 2) – GHS07; Serious eye irritation (Category 2) – GHS07; Hazardous to the aquatic environment, chronic (Category 1) – GHS09

Hazard Statements: H301 Toxic if swallowed; H332 Harmful if inhaled; H315 Causes skin irritation; H319 Causes serious eye irritation; H410 Very toxic to aquatic life with long lasting effects

UN Number: UN 2810

Hazard Class: 6.1

Packing Group: III