Aure Chemical: Trusted Source of 2-Chloromethyl-1,3-dioxolane CAS 2568-30-1
2-Chloromethyl-1,3-dioxolane is a specialized organic intermediate widely used in fine chemical and pharmaceutical manufacturing. As a stable, protected form of chloroacetaldehyde, it enables controlled introduction of the chloromethylcarbonyl group in complex synthetic sequences. Aure Chemical maintains consistent quality and full documentation to support laboratory and scale-up requirements.
Basic Information
| CAS No. | 2568-30-1 |
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| EC No. | 219-908-5 |
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| Linear Formula | ClCH2CH(OCH2CH2)O |
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| Molecular Weight | 122.55 |
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| Appearance | Colorless to light yellow clear liquid |
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| Melting Point | Not available |
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| Boiling point | 157-158 °C (lit.) |
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| Density | 1.234 g/mL at 25 °C (lit.) |
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| Solubility | Insoluble in water; soluble in common organic solvents (chloroform, ethyl acetate, ethanol) |
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| Storage Conditions | Keep in a tightly closed container in a cool, dry place. Protect from light and moisture. |
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| Chemical Structure |  |
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Key Applications
Organic synthesis intermediate: 2-Chloromethyl-1,3-dioxolane serves as a masked chloroacetaldehyde building block for nucleophilic substitution and carbonyl transformations under mild conditions.
Fine chemical intermediate: It is utilized in the preparation of specialty fine chemicals that require acetal-protected chloromethyl functionality.
Pharmaceutical intermediate: The compound acts as a key precursor in the synthesis of pharmaceutical APIs including doxofylline and related derivatives.
Laboratory research: Researchers employ it in exploratory synthetic studies and methodology development involving protected aldehydes.
Process development: It facilitates route optimization and scale-up activities in custom synthesis projects for complex organic targets.
Why Choose Aure Chemical
Consistent product quality: Reliable material quality is supported by routine quality control to deliver batch consistency suitable for fine chemical sourcing.
Flexible global supply: Supply support for laboratory scale, pilot scale and bulk procurement is ensured through established logistics channels.
SDS and COA support: Documentation support for sourcing, export and quality review is provided with SDS and COA available upon request.
Packaging and technical service: Flexible packaging options for sample, trial and bulk supply include 25L/200L HDPE drum, moisture-protected together with professional technical communication.
